Limits and progress

Progress and limits of TSE diagnostic tools.

Following the two "mad cow" crises of 1996 and 2000, there was an urgent need for rapid and sensitive diagnostic methods to identify animals infected with the bovine spongiform encephalopathy (BSE) agent. This stimulated research in the field of prion diagnosis and led to the establishment of numerous so-called "rapid tests" which have been in use in Europe since 2001 for monitoring at-risk pop...

Generalized Covering Groups and Direct Limits

Progress and limits of PrP gene selection policy.

Classical scrapie has proved to be a notoriously difficult disease to control due to a poor understanding of its natural history. The recognition of disease risk linkage to PrP genotype has offered the prospect of a disease control strategy, viz. genotyping and selective breeding, novel to veterinary medicine when first considered in the 1990s. The UK Spongiform Encephalopathy Advisory Committe...

Education and equipment for people who smoke crack cocaine in Canada: progress and limits

BACKGROUND People who smoke crack cocaine experience a wide variety of health-related issues. However, public health programming designed for this population is limited, particularly in comparison with programming for people who inject drugs. Canadian best practice recommendations encourage needle and syringe programs (NSPs) to provide education about safer crack cocaine smoking practices, dist...

Limits in modified categories of interest

‎We firstly prove the completeness of the category of crossed modules in a modified category of interest‎. ‎Afterwards‎, ‎we define pullback crossed modules and pullback cat objects that are both obtained by pullback diagrams with extra structures on certain arrows‎. ‎These constructions unify many corresponding results for the cases of groups‎, ‎commutative algebras and can also be adapted to ...